From Fresh Leaf to Pharmaceutical-Grade Isolate
The journey from raw Southeast Asian tree leaf to a pure, chewable tablet involves cutting-edge botanical chromatography. In this article, we reveal the sophisticated 7-OH extraction process employed in ZOHM’s cGMP laboratories.
Stage 1: Supercritical Fluid Extraction
Organic Mitragyna leaf biomass is placed in high-pressure vessels where carbon dioxide (CO2) is heated and pressurized to its supercritical fluid state. This non-toxic solvent gently strips the full spectrum of lipophilic alkaloids from the cell walls.
Stage 2: Multi-Stage Flash Chromatography
The crude extract is dissolved in cold USP-grade ethanol and pumped through high-efficiency silica chromatography columns. By varying mobile phase gradients, our chemists cleanly separate 7-hydroxymitragynine from other alkaloids, yielding an isolate exceeding 98.5% purity.
The result is the pristine white-to-light-tan crystalline isolate found in our Blacked Out 120mg Tablets. Verify batch purity on our Lab Test Directory.